BIAcoustic is a research project which proposes to develop a biosensor for the analysis of bio-molecular interaction by focusing particularly on samples having a small quantity of biological materials (low concentration or low volume), used from pharmacy to medicine (drug screening, antibody therapy, neonatal tests, etc.).

The new technique that we are proposing is based on the use of functionalized oil droplets produced within a biochip as a capture surface for the bio-analytes of interest. These continuously produced droplets allow simple and low-cost renewal of the capture surface without changing the biochip, making it possible to produce reusable and low-cost sensors.

Within this sensor, the quantification of the captured bio-analytes is obtained by observing the evolution of resonances excited by acoustic waves within the droplets. This project will first require a numerical study and the creation of demonstrators to study the acoustic phenomena in the droplets before the realization of a functional biosensor using clean room techniques.

This project is held by FEMTO-ST (F Chollet and is supported by the Bourgogne Franche-Comté region and the National Research Agency (ANR):

One Ph.D student has been recruited for this project.